Detalhe da pesquisa
1.
PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum.
PLoS Pathog
; 19(7): e1011006, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523385
2.
The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites.
Traffic
; 23(9): 442-461, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040075
3.
A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell.
PLoS Pathog
; 18(2): e1009977, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192672
4.
The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.
Mol Microbiol
; 117(5): 1245-1262, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35403274
5.
Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells.
Cell Microbiol
; 23(8): e13332, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33774908
6.
The triumvirate of signaling molecules controlling Toxoplasma microneme exocytosis: Cyclic GMP, calcium, and phosphatidic acid.
PLoS Pathog
; 15(5): e1007670, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31121005
7.
Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
Bioorg Chem
; 117: 105359, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34689083
8.
Spatial organization of protein export in malaria parasite blood stages.
Traffic
; 19(8): 605-623, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29696751
9.
Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
J Biol Chem
; 291(49): 25375-25386, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738107
10.
Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150.
Cell Microbiol
; 18(11): 1551-1569, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27019089
11.
Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii.
J Biol Chem
; 288(38): 27002-27018, 2013 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913689
12.
Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX).
J Biol Chem
; 287(11): 7871-84, 2012 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22253438
13.
A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in Plasmodium falciparum through Potential Inhibition of the Parasite's PI4KIIIB Enzyme.
ACS Infect Dis
; 9(9): 1695-1710, 2023 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639221
14.
A novel family of Apicomplexan glideosome-associated proteins with an inner membrane-anchoring role.
J Biol Chem
; 284(37): 25353-63, 2009 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19561073
15.
Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes.
mBio
; 10(5)2019 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31594816
16.
A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4.
Sci Rep
; 9(1): 10292, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311978
17.
Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export.
PLoS One
; 13(11): e0204785, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30439948
18.
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate.
Elife
; 62017 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28252383
19.
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity.
J Med Chem
; 60(3): 1171-1188, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28080063
20.
A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa.
FEBS Lett
; 590(15): 2469-81, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27403735